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Adult onset alexander disease. Chapter 10

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More than mutations have been described. MG is eminently treatable; ALS is not. Mild motor delay is followed by gradual motor deterioration with ataxia and spasticity. Peripheral nerves are normally myelinated.

Further Reading

Once, AD is over a team of astrocytes. Run of Active date: Most people with ALS die of unavailable failure or momentum. Review of Job disease: Most people with ALS die of unavailable good or pneumonia.

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Neurological development is arrested and patients die in their teens. GFAP is the protein of intermediate astrocytic filaments.


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Most people with ALS die between two and four years after the diagnosis. In addition, all patients showed diffuse and symmetric white matter abnormalities in the frontal regions of the brain.

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The pathology varies with the severity and stage of the disease. As the disease advances, brain weight is reduced and white matter atrophy develops. The age of onset is 20 to 50 years old.


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